Anti-Dynactin 1(N-term) Monoclonal Antibody-蛋白质/抗原/多肽-试剂-生物在线
北京索莱宝科技有限公司
Anti-Dynactin 1(N-term)  Monoclonal Antibody

Anti-Dynactin 1(N-term) Monoclonal Antibody

商家询价

产品名称: Anti-Dynactin 1(N-term) Monoclonal Antibody

英文名称: Anti-Dynactin 1(N-term) Monoclonal Antibody

产品编号: K000007M

产品价格: 0

产品产地: 北京

品牌商标: Solarbio

更新时间: 2025-12-25T09:40:42

使用范围: null

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Anti-Dynactin 1(N-term) Monoclonal Antibody

品牌:Solarbio | 货号:K000007M
商品货号:商品品牌:规格基本售价:选择规格
K000007M-50ulSolarbio50ul960.00元
K000007M-100ulSolarbio100ul1600.00元
 
英文名称Mouse Dynactin 1(N-term) Monoclonal Antibody
应用2WB IP
克隆类型2Monoclonal Antibody
别名Dynactin 1(N-term)
应用WB,IP
稀释比例WB1:500
交叉反应Human
蛋白分子量150kDa
Gene ID1639
保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 58% Glycerol.
纯化方法Affinity purification
亚型IgG2b
免疫原Purified recombinant Dynactin 1 protein fragments expressed in E.coli
性状Lyophilized or Liquid
Swiss ProtQ14203
克隆号3D5-C6-D5
克隆类型Monoclonal Antibody
来源Mouse
背景资料This gene encodes the largest subunit of dynactin,a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150kD.Dynactin binds to both microtubules and cytoplasmic dynein.Dynactin is involved in a diverse array of cellular functions,including ER-to-Golgi transport,the centripetal movement of lysosomes and endosomes,spindle formation,chromosome movement,nuclear positioning, and axonogenesis.This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus.Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).[provided by RefSeq, Oct 2008]