Anti-Dynactin 1(N-term) Monoclonal Antibody
产品名称: Anti-Dynactin 1(N-term) Monoclonal Antibody
英文名称: Anti-Dynactin 1(N-term) Monoclonal Antibody
产品编号: K000007M
产品价格: 0
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-12-25T09:40:42
使用范围: null
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Anti-Dynactin 1(N-term) Monoclonal Antibody
品牌:Solarbio | 货号:K000007M
| 英文名称 | Mouse Dynactin 1(N-term) Monoclonal Antibody |
|---|---|
| 应用2 | WB IP |
| 克隆类型2 | Monoclonal Antibody |
| 别名 | Dynactin 1(N-term) |
| 应用 | WB,IP |
| 稀释比例 | WB1:500 |
| 交叉反应 | Human |
| 蛋白分子量 | 150kDa |
| Gene ID | 1639 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 58% Glycerol. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG2b |
| 免疫原 | Purified recombinant Dynactin 1 protein fragments expressed in E.coli |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | Q14203 |
| 克隆号 | 3D5-C6-D5 |
| 克隆类型 | Monoclonal Antibody |
| 来源 | Mouse |
| 背景资料 | This gene encodes the largest subunit of dynactin,a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150kD.Dynactin binds to both microtubules and cytoplasmic dynein.Dynactin is involved in a diverse array of cellular functions,including ER-to-Golgi transport,the centripetal movement of lysosomes and endosomes,spindle formation,chromosome movement,nuclear positioning, and axonogenesis.This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus.Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).[provided by RefSeq, Oct 2008] |
