Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein
产品名称: Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein
英文名称: Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein
产品编号: PH38996M5
产品价格: 0
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: null
安诺伦(北京)生物科技有限公司
- 联系人 :
- 地址 : 北京大兴经济技术开发区天骥智谷35A
- 邮编 :
- 所在区域 : 北京
- 电话 : 189****2642 点击查看
- 传真 : 点击查看
- 邮箱 : 3359689365@qq.com
产品概述:Recombinant protein of human BCL2-associated athanogene 4 (BAG4) 蛋白长度:Recombinant protein was produced with GoldORF clone, [GH36144V]. Click on the GoldORF clone link to view cDNA and protein sequences. 表达系统:HEK293T 种属:Human 标签类型:C-Myc/DDK 分子量:49.4 kDa 通用名:BAG4 总结:The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011] 形式:Liquid 浓度:>50 ug/mL as determined by microplate BCA method 纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol 别名:BAG-4; SODD