Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein-蛋白质/抗原/多肽-试剂-生物在线
安诺伦(北京)生物科技有限公司
Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein

Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein

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产品名称: Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein

英文名称: Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein

产品编号: PH38996M5

产品价格: 0

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: null

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产品概述:Recombinant protein of human BCL2-associated athanogene 4 (BAG4)

蛋白长度:Recombinant protein was produced with GoldORF clone, [GH36144V]. Click on the GoldORF clone link to view cDNA and protein sequences.

表达系统:HEK293T

种属:Human

标签类型:C-Myc/DDK

分子量:49.4 kDa

通用名:BAG4

总结:The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

形式:Liquid

浓度:>50 ug/mL as determined by microplate BCA method

纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

别名:BAG-4; SODD