[KO Validated] CRMP2/DPYSL2 Rabbit pAb (APR21128N)
产品名称: [KO Validated] CRMP2/DPYSL2 Rabbit pAb (APR21128N)
英文名称: [KO Validated] CRMP2/DPYSL2 Rabbit pAb (APR21128N)
产品编号: APR21128N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
安诺伦(北京)生物科技有限公司
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- 地址 : 北京大兴经济技术开发区天骥智谷35A
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分子量:Calculated MW: 58kDa/62kDa Observed MW: 62kDa 细胞定位:Cytoplasm, Membrane, cytoskeleton, cytosol 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 总结:This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.