P4HB MaxPab rabbit polyclonal antibody (D01)
产品名称： P4HB MaxPab rabbit polyclonal antibody (D01)
英文名称： P4HB MaxPab rabbit polyclonal antibody (D01)
产品编号： H00005034-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human P4HB protein.
- Immunogen:
- P4HB (NP_000909.2, 1 a.a. ~ 508 a.a) full-length human protein.
- Sequence:
- MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- P4HB MaxPab rabbit polyclonal antibody. Western Blot analysis of P4HB expression in human liver.
- Protocol Download
- Western Blot (Tissue lysate)
- P4HB MaxPab rabbit polyclonal antibody. Western Blot analysis of P4HB expression in mouse kidney.
- Protocol Download
- Western Blot (Cell lysate)
- P4HB MaxPab rabbit polyclonal antibody. Western Blot analysis of P4HB expression in Jurkat.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of P4HB expression in transfected 293T cell line (H00005034-T02) by P4HB MaxPab polyclonal antibody.
Lane 1: P4HB transfected lysate(57.10 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of P4HB transfected lysate using anti-P4HB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with P4HB purified MaxPab mouse polyclonal antibody (B01P) (H00005034-B01P).
- Protocol Download
- Entrez GeneID:
- 5034
- GeneBank Accession#:
- NM_000918.2
- Protein Accession#:
- NP_000909.2
- Gene Name:
- P4HB
- Gene Alias:
- DSI,ERBA2L,GIT,P4Hbeta,PDI,PDIA1,PHDB,PO4DB,PO4HB,PROHB
- Gene Description:
- prolyl 4-hydroxylase, beta polypeptide
- Omim ID:
- 176790
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq
- Other Designations:
- collagen prolyl 4-hydroxylase beta,glutathione-insulin transhydrogenase,procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide,prolyl 4-hydroxylase, beta subunit,protein disulfide isomerase family A, member 1,protein d
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