IDE polyclonal antibody
产品名称： IDE polyclonal antibody
英文名称： IDE polyclonal antibody
产品编号： PAB7317
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of IDE.
- Immunogen:
- A synthetic peptide corresponding to human IDE.
- Sequence:
- C-QQYNFDRDNTE
- Host:
- Goat
- Theoretical MW (kDa):
- 118, 54
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.
Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM.Neurobiol Aging. 2007 Jun;28(6):824-30. Epub 2006 Jun 12.
- Applications
- Western Blot (Cell lysate)
- IDE polyclonal antibody (Cat # PAB7317) (0.1 ug/mL) staining of K-562 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 3416
- Protein Accession#:
- NP_004960.1
- Gene Name:
- IDE
- Gene Alias:
- FLJ35968,INSULYSIN
- Gene Description:
- insulin-degrading enzyme
- Omim ID:
- 146680
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response. [provided by RefSeq
- Other Designations:
- OTTHUMP00000020097,insulinase,insulysin
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Birth Weight
- Carcinoma
- Cardiovascular Diseases
- Cognition
- Cognition Disorders
- Diabetes Complications
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetes, Gestational
- Diabetes, type 1
- Down Syndrome
- Edema
- Genetic Predisposition to Disease
- Glucose Intolerance
- Glucose Metabolism Disorders
- Hyperglycemia