Anti-ABL1 Polyclonal Antibody

品牌：solarbio | 货号：K001657P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001657P-50ul	solarbio	50ul	960.00元
K001657P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-ABL1 Polyclonal Antibody
别名 ABL;JTK7;bcr/abl;c-ABL;c-ABL1;p150;v-abl
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:100-200. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 123kDa
Gene ID 25
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human ABL1
性状 液体
Public Immunogen Range A synthetic peptide of human ABL1
Subcellular Locations Cytoplasm Lipid-anchor Mitochondrion Nucleus Nucleus membrane cytoskeleton
Swiss Prot P00519
克隆类型 Polyclonal Antibody
背景资料 This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.

英文名称	Anti-ABL1 Polyclonal Antibody
别名	ABL;JTK7;bcr/abl;c-ABL;c-ABL1;p150;v-abl
应用	WB IHC IF
稀释比例	WB 1:500-2000. IHC 1:100-200. IF 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	123kDa
Gene ID	25
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human ABL1
性状	液体
Public Immunogen Range	A synthetic peptide of human ABL1
Subcellular Locations	Cytoplasm Lipid-anchor Mitochondrion Nucleus Nucleus membrane cytoskeleton
Swiss Prot	P00519
克隆类型	Polyclonal Antibody
背景资料	This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.