FBN1 (Human) Recombinant Protein (Q01)
产品名称： FBN1 (Human) Recombinant Protein (Q01)
英文名称： FBN1 (Human) Recombinant Protein (Q01)
产品编号： H00002200-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Human FBN1 partial ORF ( NP_000129, 2772 a.a. - 2871 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- SNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH
- Theoretical MW (kDa):
- 36.74
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- Anti-fibrillin-1 autoantibodies in normal pregnancy and recurrent pregnancy loss.
Atanasova MA, Konova EI, Aleksovska TA, Todorova KN, Georgieva MN, Lukanov TH.Autoimmun Rev. 2010 Sep 17. [Epub ahead of print]
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2200
- GeneBank Accession#:
- NM_000138
- Protein Accession#:
- NP_000129
- Gene Name:
- FBN1
- Gene Alias:
- FBN,MASS,MFS1,OCTD,SGS,WMS
- Gene Description:
- fibrillin 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq
- Other Designations:
- fibrillin 15
- Related Disease
- Aneurysm, Dissecting
- Aortic Aneurysm
- Aortic Aneurysm, Abdominal
- Aortic Aneurysm, Thoracic
- Aortic Rupture
- Aortic Valve Insufficiency
- Aortic Valve Stenosis
- Bipolar Disorder
- Cardiovascular Diseases
- Connective Tissue Diseases
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Dilatation, Pathologic
- Ectopia Lentis
- Edema
- Exfoliation Syndrome
- Genetic Predisposition to Disease
- Glaucoma
- Glaucoma, Open-Angle