NFKB2 (phospho S865) polyclonal antibody
产品名称: NFKB2 (phospho S865) polyclonal antibody
英文名称: NFKB2 (phospho S865) polyclonal antibody
产品编号: PAB25236
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of NFKB2.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding S865 of human NFKB2.
- Sequence:
- E-D-Sp-A-Y
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Affinity chromatography
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 4791
- Protein Accession#:
- Q00653
- Gene Name:
- NFKB2
- Gene Alias:
- LYT-10,LYT10
- Gene Description:
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- Omim ID:
- 164012
- Gene Ontology:
- Hyperlink
- Gene Summary:
- NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. For reviews, see Chen et al. (1999) [PubMed 9895331] and Baldwin (1996) [PubMed 8717528].[supplied by OMIM
- Other Designations:
- OTTHUMP00000020371,OTTHUMP00000059136,nuclear factor of kappa light chain gene enhancer in B-cells 2,nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Bronchiolitis, Viral
- Calcinosis
- Cardiovascular Diseases
- Connective Tissue Diseases
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Edema
- Fetal Diseases
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Infant, Premature, Diseases
- Inflammation