Anti-SMC1A(C-term) Monoclonal Antibody

品牌：solarbio | 货号：K001355M

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001355M-50ul	solarbio	50ul	960.00元
K001355M-100ul	solarbio	100ul	1600.00元

英文名称	Anti-SMC1A(C-term) Monoclonal Antibody
别名	CDLS2;DXS423E;SB1.8;SMC1;SMC1alpha;SMC1L1;SMCB
应用	WB ICC
稀释比例	WB 1:1000. IHC 1:100.
交叉反应	Human
蛋白分子量	143kDa
Gene ID	8243
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human SMC1A(C-term.) protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human SMC1A(C-term.) protein fragments expressed in E.coli.
Subcellular Locations	Chromosome Nucleus centromere kinetochore
Swiss Prot	Q14683
克隆号	4C5-C8-A11
克隆类型	Monoclonal Antibody
背景资料	Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq, Jul 2008]