产品概述：Purified recombinant protein of Human mediator complex subunit 28 (MED28), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

蛋白长度：A DNA sequence encoding human full-length MED28

表达系统：E. coli

种属：Human

标签类型：N-His

分子量：19.3 kDa

通用名：MED28

总结：Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.[UniProtKB/Swiss-Prot Function]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.

别名：1500003D12Rik; EG1; magicin